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Forschung

Musculosceletal Tumor Unit (CCC-MST)

Klinische Studien

Laufende klinische Studien

  • A phase 2, double-blind, placebo-controlled study evaluating the safty and efficacy of IPI-926 in patients with metastatic or locally advanced (unresectable) chondrosarcoma.
  • A randomized, double-blind, placebo-controlled phase III study of regorafenib plus best supportive care versus placebo plus best supportive care for subjects with metastatic and/or unresectable gastrointestinal stroma tumors (GIST) whose disease  has progressed despite prior treatment with at least imatinib and sunitinib.
  • A randomized, open-label, multi-center phase III study to evaluate the efficacy and safety of nilotinib versus imatinib in adult patients with unresectable or metastatic gastrointestinal stromal tumors (GIST).
  • A randomized, open-label, multicenter, phase III study to compare the efficacy and safety of eribulin with dacarbazine in subjects with soft tissue sarcoma.
  • An open label, multi-center, phase 2 study of Denosumab in subjects with giant cell tumor of bone. (Recruiting closed!)
  • CWS-2007-HR – Randomisiere Phase-III-Studie der Cooperativen Weichteilsarkom Studien-gruppe für lokalisierte Hochrisiko-Rhabdomyosarkome und lokalisierte rhabdomyosarkomartige Weichteiltumore bei Kindern, Jugendlichen und jungen Erwachsenen (EudraCT 2007-001478-10).
  • CWS-SoTiSaR – Register für Weichteilsarkome und seltene Weichteiltumore.
  • Determination of prognostic MRI features, and evaluation of chemotherapy response in primary malignant bone tumours by MRI, compared to 18-F-FDG-PET/CT.
  • Efficacy, safety and tolerability of adjuvant Glivec® (Imatinib) in adult GIST patients within the approved label in Austria.
  • EURAMOS 1 – A randomized trial of the European and American Osteosarcoma Study Group to optimize treatment strategies for resectable osteosarcoma based on histological response to pre-operative chemotherapy (Rekrutierung beendet am 30.06.2011).
  • EWING 2008 – Ewing Tumoren, prospektive, randomisierte, internationale, multizentrische Phase 3 Studie (EudraCT 2008-003658-13).
  • Histologische Analyse von Immunozyten in Osteosarkomen.
  • Knochendichte und Frakturrate bei langzeitüberlebenden Ewingsarkompatienten.
  • Kooperation im Rahmen des internationalen Tumorprothesenregisters.
  • LCH III – Langerhanszell Histiozytose, Therapieoptimierungsstudie.
  • Navigationsassistierte Resektion von Knochentumoren.
  • Retrospektive klinische Studien von Tumoren des Bewegungsapparates im Rahmen des Wiener Knochen- und Weichteilgeschwulstregisters.
  • T2-mapping chondrogener Tumore.
  • TRUST: A phase IIb/III multicenter study comparing the efficacy of Trabectedin administered as a 3-hour or 24-hour infusion to doxorubicin in patients with advanced or  metastastic untreated soft tissue sarcoma.

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