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Grundlagenforschung

Musculosceletal Tumor Unit (CCC-MST)
  1. Comprehensive Cancer Center
  2. Forschung
  3. CCC-Units
  4. Musculosceletal Tumor Unit
  5. Forschung
  6. Grundlagenforschung

Laufende Projekte

  • ASSET – Analysing and Striking the Sensitivities of Embryonal Tumours (EU-FP7 gefördertes Systembiologieprojekt #259348).
  • EWS/EWS-FLI1 in der post-transkriptionellen Genregulation (FWF  20665-B12).
  • Mechanismen der transkriptionellen Kontrolle durch EWS-FLI1 (FWF 22328-B09).
  • Mechanisms of target regulation by the chimeric oncogene EWS-FLI1 in Ewing´s sarcoma (ÖAW DOC-FORTE 22882).
  • Präklinische Entwicklung neuer experimenteller Osteosarkom-Therapie anhand experimenteller Gallium-Verbindungen, Zoledronsäure und bone-targeting platinum drugs.
  • The EGFR inhibitor Gefitinib sensitizes osteosarcoma cells against anthracycline-based chemotherapy.
  • The interplay of NF-KB, HIF-1? and EWS-FLI1 in Ewing’s sarcoma family tumors” (ÖNB 14205).
  • Unraveling the mechanisms of resistance to Hedgehog pathway inhibitors in chondrosarcoma.