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2023

Exemplarisch für unsere Forschungsarbeit möchten wir hier einige unserer Forscher:innen und ihre Arbeiten präsentieren.

Synthesis and Preclinical Evaluation of Radiolabeled [103Ru]BOLD-100

Petra Heffeter, Zentrum für Krebsforschung ©MedUni Wien
Petra Heffeter, Zentrum für Krebsforschung

Happl, B., Brandt, M., Balber, T., Benčurová, K., Talip, Z., Voegele, A., Heffeter, P., Kandioller, W., Van der Meulen, N. P., Mitterhauser, M., Hacker, M., Keppler, B. K., & Mindt, T. L. (2023). Synthesis and Preclinical Evaluation of Radiolabeled [103Ru]BOLD-100. Pharmaceutics, 15(11), 2626. https://doi.org/10.3390/pharmaceutics15112626

Impact of BMI in Patients With Early Hormone Receptor-Positive Breast Cancer Receiving Endocrine Therapy With or Without Palbociclib in the PALLAS Trial

Doktorin Christine Deutschmann ©MedUni Wien
Christine Deutschmann, Frauenheilkunde

Pfeiler G, Hlauschek D, Mayer EL, Deutschmann C, Kacerovsky-Strobl S, Martin M, Meisel JL, Zdenkowski N, Loibl S, Balic M, Park H, Prat A, Isaacs C, Bajetta E, Balko JM, Bellet-Ezquerra M, Bliss J, Burstein H, Cardoso F, Fohler H, Foukakis T, Gelmon KA, Goetz M, Haddad TC, Iwata H, Jassem J, Lee SC, Linderholm B, Los M, Mamounas EP, Miller KD, Morris PG, Munzone E, Gal-Yam EN, Ring A, Shepherd L, Singer C, Thomssen C, Tseng LM, Valagussa P, Winer EP, Wolff AC, Zoppoli G, Machacek-Link J, Schurmans C, Huang X, Gauthier E, Fesl C, Dueck AC, DeMichele A, Gnant M; PALLAS Groups and Investigators. Impact of BMI in Patients With Early Hormone Receptor-Positive Breast Cancer Receiving Endocrine Therapy With or Without Palbociclib in the PALLAS Trial. J Clin Oncol. 2023 Nov 20;41(33):5118-5130. https://doi.org/10.1200/JCO.23.00126 . Epub 2023 Aug 9. PMID: 37556775.

Sustained Survival Benefit in Recurrent Medulloblastoma by a Metronomic Antiangiogenic Regimen: A Nonrandomized Controlled Trial

Andreas Peyrl, Universitätsklinik für Kinder- und Jugendheilkunde, zur MEMMAT-Studie ©Comprehensive Cancer Center Vienna
Andreas Peyrl, Kinder- und Jugendheilkunde

Peyrl, A., Chocholous, M., Sabel, M., Lassaletta, A., Sterba, J., Leblond, P., Nysom, K., Torsvik, I., Chi, S. N., Perwein, T., Jones, N., Holm, S., Nyman, P., Mörse, H., Öberg, A., Weiler-Wichtl, L., Leiss, U., Haberler, C., Schmook, M. T., Mayr, L., … Slavc, I. (2023). Sustained Survival Benefit in Recurrent Medulloblastoma by a Metronomic Antiangiogenic Regimen: A Nonrandomized Controlled Trial. JAMA oncology, 10.1001/jamaoncol.2023.4437. Advance online publication. https://doi.org/10.1001/jamaoncol.2023.4437

Targeting YB-1 via entinostat enhances cisplatin sensitivity of pleural mesothelioma in vitro and in vivo

Karin Schelch ©MedUni Wien
Karin Schelch, Thoraxonkologisches translationales Forschungslabor

Schelch, K., Emminger, D., Zitta, B., Johnson, T. G., Kopatz, V., Eder, S., Ries, A., Stefanelli, A., Heffeter, P., Hoda, M. A., Hoetzenecker, K., Dome, B., Berger, W., Reid, G., & Grusch, M. (2023). Targeting YB-1 via entinostat enhances cisplatin sensitivity of pleural mesothelioma in vitro and in vivo. Cancer letters, 574, 216395. https://doi.org/10.1016/j.canlet.2023.216395

The Impact of Adjuvant Radiotherapy on Immediate Prepectoral Implant-Based Breast Reconstruction

Larissa Nixdorf ©MedUni Wien
Larissa Nixdorf, Allgemeinchirurgie

Ostapenko, E., Nixdorf, L., Devyatko, Y., Exner, R., Wimmer, K., & Fitzal, F. (2023). The Impact of Adjuvant Radiotherapy on Immediate Prepectoral Implant-Based Breast Reconstruction. Aesthetic plastic surgery, 10.1007/s00266-023-03661-z. Advance online publication. https://doi.org/10.1007/s00266-023-03661-z

Young oncologists' perspective on the role and future of the clinician-scientist in oncology

Anna Sophie Berghoff, Innere Medizin I

Lim, K. H. J., Westphalen, C. B., Berghoff, A. S., Cardone, C., Connolly, E. A., Güven, D. C., Kfoury, M., Kocakavuk, E., Mandó, P., Mariamidze, E., Matikas, A., Moutafi, M., Oing, C., Pihlak, R., Punie, K., Sánchez-Bayona, R., Sobczuk, P., Starzer, A. M., Tečić Vuger, A., Zhu, H., … Amaral, T. (2023). Young oncologists' perspective on the role and future of the clinician-scientist in oncology. ESMO open, 8(5), 101625. Advance online publication. https://doi.org/10.1016/j.esmoop.2023.101625

Differences in future life expectancy of testicular germ-cell tumor patients vs. age-matched male population-based controls

Morra, S., Piccinelli, M. L., Cano Garcia, C., Tappero, S., Barletta, F., Incesu, R. B., Scheipner, L., Baudo, A., Tian, Z., Saad, F., Mirone, V., Califano, G., Colla' Ruvolo, C., Shariat, S. F., de Cobelli, O., Musi, G., Chun, F. K. H., Terrone, C., Briganti, A., Tilki, D., … Karakiewicz, P. I. (2023). Differences in future life expectancy of testicular germ-cell tumor patients vs. age-matched male population-based controls. International urology and nephrology, 10.1007/s11255-023-03763-2. Advance online publication. https://doi.org/10.1007/s11255-023-03763-2

Explaining risks and benefits of loco-regional treatments to patients

Beltran-Bless, A. A., Kacerovsky-Strobl, S., & Gnant, M. (2023). Explaining risks and benefits of loco-regional treatments to patients. Breast (Edinburgh, Scotland), 71, 132–137. Advance online publication. https://doi.org/10.1016/j.breast.2023.08.006

Mutational landscape of intestinal crypt cells after long-term in vivo exposure to high fat diet

Meyenberg, M., Hakobyan, A., Papac-Milicevic, N., Göderle, L., Langner, F. L., Markovic, M., Lee, J. H., Koo, B. K., Busslinger, G. A., da Silva, I. T., Binder, C. J., Menche, J., & Loizou, J. I. (2023). Mutational landscape of intestinal crypt cells after long-term in vivo exposure to high fat diet. Scientific reports, 13(1), 13964. https://doi.org/10.1038/s41598-023-41123-3

LM02 trial Perioperative treatment with panitumumab and FOLFIRI in patients with wild-type RAS, potentially resectable colorectal cancer liver metastases-a phase II study

Piringer, G., Gruenberger, T., Thaler, J., Kührer, I., Kaczirek, K., Längle, F., Viragos-Toth, I., Amann, A., Eisterer, W., Függer, R., Andel, J., Pichler, A., Stift, J., Sölkner, L., Gnant, M., & Öfner, D. (2023). LM02 trial Perioperative treatment with panitumumab and FOLFIRI in patients with wild-type RAS, potentially resectable colorectal cancer liver metastases-a phase II study. Frontiers in oncology, 13, 1231600. https://doi.org/10.3389/fonc.2023.1231600

Immune Checkpoint Inhibitors for Child-Pugh Class B Advanced Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis

Bernhard Scheiner, Innere Medizin III

Xie, E., Yeo, Y. H., Scheiner, B., Zhang, Y., Hiraoka, A., Tantai, X., Fessas, P., de Castro, T., D'Alessio, A., Fulgenzi, C. A. M., Xu, S., Tsai, H. M., Kambhampati, S., Wang, W., Keenan, B. P., Gao, X., Xing, Z., Pinter, M., Lin, Y. J., Guo, Z., … Ji, F. (2023). Immune Checkpoint Inhibitors for Child-Pugh Class B Advanced Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis. JAMA oncology, e233284. Advance online publication. https://doi.org/10.1001/jamaoncol.2023.3284